3-Fluoro-4-chlorophenylmagnesium bromide
4-chloro-3-fluorophenylmagnesium bromide
CAS: 170793-00-7
Molecular Formula: C6H3BrClFMg
3-Fluoro-4-chlorophenylmagnesium bromide - Names and Identifiers
3-Fluoro-4-chlorophenylmagnesium bromide - Physico-chemical Properties
| Molecular Formula | C6H3BrClFMg |
| Molar Mass | 233.75 |
| Density | 0.968g/mLat 25°C |
| Boling Point | 65°C |
| Flash Point | 1°F |
| Vapor Presure | 9.22mmHg at 25°C |
| Appearance | Liquid |
| Color | Yellow to brown |
| Storage Condition | 2-8°C |
| Sensitive | Air & Moisture Sensitive |
| Physical and Chemical Properties | WGK Germany:1 |
3-Fluoro-4-chlorophenylmagnesium bromide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R22 - Harmful if swallowed R34 - Causes burns R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2924 3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29310099 |
| Hazard Note | Flammable |
| Hazard Class | 3 |
3-Fluoro-4-chlorophenylmagnesium bromide - Introduction
Brmide is an organic compound with the chemical formula C6H4ClFBrMg. The following is a description of the properties, uses, methods of manufacture and safety information of the bromide:
Nature:
-Appearance: bromide is a colorless or pale yellow solid.
-Melting point: About 150-155 ° C.
-Solubility: Soluble in some organic solvents, such as ether and tetrahydrofuran.
-Stability: Stable in air, but avoid exposure to moisture.
Use:
-bromide is an important reagent in organic synthesis and can be used in various chemical reactions.
-It can be used as a Grignard reagent to replace halogens on aromatic compounds, such as bromine and fluorine.
-bromide can also be used to synthesize other organic compounds, such as arylthioethers and arylamino compounds.
-It is also used in the fields of drug synthesis and pesticide synthesis.
Method:
-bromide can be synthesized by Grignard reaction. First, magnesium flakes are reacted with an organic bromide to produce an organic magnesium reagent. The organomagnesium reagent is then reacted with fluorophenyl bromide to give fluoromide.
Safety Information:
-bromides are organic compounds that are hazardous chemicals.
-Chemical safety practices should be observed during use and storage.
-Avoid direct contact with skin, eyes and respiratory tract. If contact is not careful, rinse with plenty of water in time.
-In solid form, avoid contact with combustibles and oxidants to prevent fire or explosion.
-When handling and disposing of waste, follow local regulations.
Please note that the above information is for reference only. For specific applications and operations, please follow the safety data sheets and professional guidance of the relevant chemicals.
Nature:
-Appearance: bromide is a colorless or pale yellow solid.
-Melting point: About 150-155 ° C.
-Solubility: Soluble in some organic solvents, such as ether and tetrahydrofuran.
-Stability: Stable in air, but avoid exposure to moisture.
Use:
-bromide is an important reagent in organic synthesis and can be used in various chemical reactions.
-It can be used as a Grignard reagent to replace halogens on aromatic compounds, such as bromine and fluorine.
-bromide can also be used to synthesize other organic compounds, such as arylthioethers and arylamino compounds.
-It is also used in the fields of drug synthesis and pesticide synthesis.
Method:
-bromide can be synthesized by Grignard reaction. First, magnesium flakes are reacted with an organic bromide to produce an organic magnesium reagent. The organomagnesium reagent is then reacted with fluorophenyl bromide to give fluoromide.
Safety Information:
-bromides are organic compounds that are hazardous chemicals.
-Chemical safety practices should be observed during use and storage.
-Avoid direct contact with skin, eyes and respiratory tract. If contact is not careful, rinse with plenty of water in time.
-In solid form, avoid contact with combustibles and oxidants to prevent fire or explosion.
-When handling and disposing of waste, follow local regulations.
Please note that the above information is for reference only. For specific applications and operations, please follow the safety data sheets and professional guidance of the relevant chemicals.
Last Update：2024-04-09 21:01:54
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